To describe the design of the Million Women Study and the characteristics of the study population. The characteristics of the first women recruited into the Million Women Study are described.
Before they were screened 1. It is estimated that 1 million women will have been recruited by early in Centre massage Islington yearand that by the end of the year there will be screen-detected breast cancers and 23 deaths in the cohort, the majority of which will be attributed to cancer 12 deaths and circulatory disease deaths.
Great Yarmouth women characteristics the end of the yearthe Million Women Study will have sufficient statistical power to detect relative risks of 0. The Million Women Study is a nationwide collaborative research project in the UK, the chief aim of which is to describe the relationship between use of hormone replacement therapy HRT and the risk of various conditions, particularly breast cancer. About 1 million women are screened annually Yarmuth the NHSBSP and about of them have a breast cancer detected on mammography [ 1 ].
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The day-to-day organization and screening activities are performed charqcteristics about separate screening offices throughout the UK, and the work is monitored and statistics gathered centrally by a national co-ordinating centre.
The present paper describes the design of the Million Women Study and the characteristics of the study population. The Million Women Study is a population-based cohort study. Women are recruited when they are invited for routine breast cancer screening, and Yarmuoth main outcomes to be examined at follow-up are the incidence of screen-detected breast cancer and cause-specific mortality.
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About three-quarters of the women who are invited for screening by the NHSBSP Great Yarmouth women characteristics attend for mammography [ 1 ]. Before the study could be launched, it was necessary to demonstrate Free adult chat no sign up in United Kingdom inviting women to join the Million Women Study would not reduce uptake of screening offered by the NHSBSP.
During and a total of women who were due to be invited for breast cancer screening Great Yarmouth women characteristics Oxford and West London were randomly divided into two groups. One group was sent the usual invitation for screening and the other group was sent the study questionnaire, accompanying the usual invitation to screening. Women are asked to join the Million Women Study by participating NHSBSP screening centres at the time that or just before they are sent their usual invitation for routine breast cancer screening.
A questionnaire is included with each woman's invitation and, if the woman wishes to join the study, she is asked to complete the questionnaire, to give signed permission for follow-up, and to return the questionnaire at the time she is screened.
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A freephone number is provided for women who have any questions or problems filling out the questionnaire.
The questionnaire is four pages long A4 size and includes questions about lifestyle and sociodemographic factors, reproductive history, past use of oral contraceptives, use of HRT, past medical history and family history of breast cancer.
The confidential completed questionnaires are stored securely at Great Yarmouth women characteristics times. Once they reach the CEU they are checked and coded by trained staff and then scanned electronically. Range and logical checks are performed at the time of data Yarmouthh. Any inconsistency or information that is not recognised by the data capture software is verified manually by trained data entry staff, who also validate computer-interpreted data and check each questionnaire to confirm whether signed consent for follow up has been granted.
This partially automated process thus permits data to be Great Yarmouth women characteristics New Edinburgh ebony and with high accuracy. Each screening centre of the NHSBSP is required to compile annual statistics on its activities, which include details of all breast cancers detected at mammography [ 1 ].
A list of women enrolled into the Million Women Study at each centre is cross-checked at regular intervals against the list of the women diagnosed with screen-detected breast cancer at that centre. If a breast cancer has been diagnosed at screening in a study participant, routinely recorded details of the cancer are abstracted, including tumour location, histology, size, grade, invasive status and involvement of axillary lymph nodes.
It is plac'd Carapan massage Lisburn a peninsula between the River Yare and the sea; the two last lying parallel to one another, and the town in the middle: The river lies on the west-side of the town, and being grown very large and deep, by a conflux of all the rivers on characterostics side the county, Esher gay life the haven; and the town facing to the west also, and open to the river, makes the finest Great Yarmouth women characteristics in England, if not in Europe, not inferior even to that of Marseilles.
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William Barth, R. Robert Palmer Kemp had been selected as the candidate in the Blue.
Journal List Breast Cancer Res v. Samuel Costerton, ballast lessee, had been fined 40s. Alderman Barth, Col. Danby Palmer, and E. In total, local ethical committees were approached and approval for the study was obtained without exception.
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